AKIPRESS.COM - Expanding clusters of the new coronavirus were eyed warily Wednesday as the outbreak upended daily life and reshaped everything from the United States presidential race to Pope Francis’ travel, AP reports.

In the U.S., the caseload passed 1,000, and outbreaks on both sides of the country were stirring alarm, while in Europe, an increasingly locked-down Italy counted more than 10,000 infections and recorded soaring deaths among its aging population.

“Right now, the epicenter — the new China — is Europe,” said Robert Redfield, the head of the U.S. Centers for Disease Control and Prevention.

Rome’s usual boisterous hum was reduced to a whisper as Italy’s 62 million people were told to mostly stay home. Though shops, cafes and restaurants remained open, police around the country were enforcing rules that customers stay 1 meter (3 feet) apart and certain businesses shutter by 6 p.m.

Authorities said 631 people have died of COVID-19 in Italy, with an increase of 168 fatalities recorded Tuesday. The health crisis was dealing a serious blow to the country’s economy — the third-largest of the 19 countries using the euro — and threatened instability worldwide.